Benfotiamine (Fat-Soluble B1): Benefits and Why It’s So Unique
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I’m sure you heard about this benine vitamin so what’s all the hype in do we really need it and what is it good for botam is a fat sble B1 normally B1 called thiamine is water sble and so there’s several advantages of having this vitamin in a fat cable form number one it can penetrate membranes that are made out of fat much easier like by a factor of 360% more penetration so benine is really good for anything neurological anything brain especially peripheral neuropathy where you have the bottom of your feet tingling numbness burning or that could be on the hands as well so what is it actually doing one of the big things it’s doing it’s inhibiting the formation of something called ages that stands for advanced glycation and products now what is that well that’s basically this uh formation of sugar with a protein or sugar with fat that’s um morphed into this unusable protein so for example when you are a diabetic and you test for blood glucose levels a lot of times they’ll do what’s called A1C and that test measures for this term glycation which basically means how much damage to your proteins in your blood is occurring like the hemoglobin is protein right so they can measure how much of that protein is unusable because it’s glycated because all the sugar interacts with the protein and kind of fuses it to make it unavailable and so as the red blood cells is UN available guess what you get you get a lot of complications from that one being just lowered amount of the ability to carry oxygen and think about the Cascade of effects that that can create also this glycation starts to accumulate in the mitochondria and it plugs up the machinery for your cells so benine is a very potent antioxidant type nutrient that inhibits the formation of this glycation it also supports the myin sheath that outer covering of the nerve that allows the nerve to actually work and on a deeper level we need B won desperately for several enzymes in our mitochondria involved in metabolism certain enzymes are dependent on B1 and if your cells don’t have B1 boy all sorts of issues start occurring so a lot of the complications especially from diabetes occur because of this lack of this B1 because the more glucose you have flowing through your bloodstream the more B1 you need so by being a diabetic you’re basically sucking up all that residual B1 that you had leaving you high and dry now there are four main tissues in the body that are affected by diabetes more than any other tissues in the body okay we have the nerve and the Brain kind of the same tissue we have the arteries we have the eye and we have the kidney now what’s so unique about these four tissues well number one they’re the most metabolically demanding tissues of your body which means they hog a lot of fuel and they also require a lot of oxygen and then they as a byproduct they put out a lot of oxidation so that means these four tissues are very susceptible to problems with too much oxidation and basically that means that your balance of antioxidants versus your oxidants are out of balance you don’t have enough antioxidants to handle the amount of oxidation occurring and you can kind of think about oxidation is kind of something rusting out in the body and so the term for that is called oxidative stress so these four tissues are very susceptible to becoming damaged with high levels of sugar because of the oxidation and the uh inability to repair and so B1 can come in there to the rescue and lower this oxidation because it’s kind of a very potent antioxidant another thing that happens in diabetes is um you have damage to the micro circulation the tiny capillaries that feed these tissues these capillary walls start to leak and you get bleeding and you especially see this in arteries you see this in the eyes it happens in the kidney and so in a deeper level we’re getting all this glycated protein junk that’s accumulating in the mitochondria plugging everything up and literally starving the cells of fuel and oxygen that’s why you see periphal neuropathy showing up as a kind of a one of the first things because it affects the extremities at the farthest distance from the heart this Advanced glycation n product compound that’s plugging everything up can come from several things it comes from eating sugar with protein when it’s cooked it comes from eating sugar and fat when it’s cooked that would be like ice cream would be a perfect example it comes from cooking in high Heats like you’re deep frying something or you’re grilling something where something is very crispy you do get a certain amount of glycation but just being a diabetic causes high levels of glycation as you get older you have more glycation so age is a big factor if you smoke if you drink alcohol and the more inflammation you have the more glycation you’re going to have this is why benot toine for diabetics is so vitally important because it basically just starts slowing down this glycation process and getting rid of the complications from diabetes and of course hopefully that person is getting rid of the real cause of diabetes which is the diet but sometimes the doctors don’t really emphasize that they’re all about managing your blood sugars well eventually need to fix the cause but also benine can help you with the symptoms along the way and also many times people combine alphalipoic acid with botam because they’re a bit synergistic alphalipoic acid directly targets inflammation as well as that oxidative stress whereas botam does that as well but it also uh supplies you with the necessary B1 for the enzymes in the mitochondria as well as directly inhibiting the formation of that glycation now inside your arteries okay uh you have this inside layer of the artery and it’s it’s called the tuna intima which means innermost layer and in that layer there’s a superficial layer of cells and they’re just like one cell thick that are exposed to blood going through the arteries and that’s called the endothelial layer that layer of cells boy that controls blood pressure it controls all sorts of hormonal interactions it gets hammered with this oxidative stress and then you start getting inflammation and you start getting scar tissue and then you start getting more clots one of the things that it does is it helps to prevent clots but if it becomes damaged you start getting clots and there’s also micro uh blood vessels that are supplying the artery walls those are called Vasa vasorum which means the vessels of the vessels so the blood vessels also need blood to survive and so all this high level of concentrated sugar in that area starts to create inflammation in those vessels which are a little bit deeper and then you start getting thickening of the arteries and stiffness of the arteries which is not just going to lead to blood pressure problems but a constriction of blood that’s flowing through the arteries in other words insulin is anti- atherosclerosis in other words it prevents this whole Cascade a problem wait a second I thought that too much insulin is bad well it is but you have this other factor involved it’s called insulin resistance so a lot of these complications that are occurring from high glucose and high insulin are occurring because you actually have a deficiency of insulin because of the resistance because the body makes more but it never actually gets to the right target to allow things to occur and so by doing things to get rid of insulin resistance you actually get more insulin to heal this whole area so by eating things that increase insulin it never is a good solution we have the arteries that are involved we also have the kidneys that get destroyed and so when you have this kidney filter that gets destroyed you start getting this leakiness in the filter so the holes become bigger and then protein kind of goes out and then sugar