Cardiologist (Dr. Nadir Ali) Explains LDL Bad Cholesterol Spike With Keto – Dr.Berg

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hey everyone welcome back and today we have a real special guest dr. nadir Ali is here and he is a keto friendly cardiologist from Houston Texas so welcome welcome to this channel can you hear me I I can hear you well okay great thank you I am honored to be here on this channel and I’m honored to be a part of your program and as I told you I have had a long-held admiration for you many of my patients are avid fans of yours and your Friday podcast so they look forward to it they come and give me all kinds of feedback I have learned how to communicate with my patients based on what you do to some degree Wow Wow thank you that’s awesome well I’m really a pleasure to meet you meet you in person or actually sort of through the line internet lines here you know just for everyone’s knowledge you’re gonna be one of the main speakers at our next Quito summit coming up in August at the end of August August 31st and September 1st it’s uh I think it’s Labor Day weekend and we’re gonna have a blast so I’m really excited to have you come out and speak you know you you bring to the table something very unique I mean you know one of the big things right now hot topics is this cholesterol thing and the LDL and people are concerned and you see these things in the in the news where oh don’t to key though it’s gonna raise your cholesterol and you’re gonna die have a heart attack yeah I yeah and so I’m coming just from your field I mean I guess that’s what what you’re taught right in school like I guess the whole cholesterol dogma has been pushed so much it’s so ingrained in us that it’s sometimes it’s hard to look at the actual data what’s your what’s your thought on that that’s like delving right into it and I’m glad you’re doing it that way because we don’t waste time in unnecessary stuff exactly but I’ve been practicing for almost 30 years and as a cardiologist and the dogma that has been taught to us is that low cholesterol low LDL is one of the best things for you to do and unfortunately if you compile all information about optimal human nutrition about human brain size about what we need to eat and how we need to behave to reduce our LDL cholesterol C Nevitt ibly it’s going to lead to very poor health it’s gonna lead to obesity insulin resistance diabetes hypertension all the chronic diseases that are going to reduce your quality of life that’s gonna make you die earlier and so I was kind of surprised that there’s such a huge paradox between LDL cholesterol and every other biomarker of health you can take anyone you know they go in opposite direction if you want to improve your insulin resistance your LDL is going to go up if you want to reduce your weight your LDL is going to go up interesting interesting so I started thinking about this as a paradox but then when you put everything together you understand that that’s how our body is probably designed to behave and so I go out there now for the last five years it took me time to understand why LDL goes up on a low-carb diet and it took me time to understand that that is not necessarily bad and in some ways having higher LDL cholesterol with very good other biomarkers might be something to celebrate not my own and I could elaborate on some of that but I wanted more interaction I wondered you to kind of chime in and say hey I want to lead this podcast in this direction yeah exactly because I wanted to there’s some there’s some things that I’m interested in personally that I would like to know your viewpoint on you know cholesterol LDL this is called bad cholesterol but really it’s a it’s a cargo ship it’s a transport ship and it delivers cholesterol we need cholesterol I’m hoping that most people know that our body makes cholesterol but what I’m interested to just start off with talking about is your take on LDL actually carries I think all of the fat soluble vitamins but I’m an a de K k1 and k2 have you seen any data on that especially even vitamin e to as an antioxidant I think it does the data on this is kind of not at least I’m not aware of some very good data on that okay that vitamin D does have its own carrier protein and that may be the LDL is a secondary mechanism for carrying vitamin D around but I guess one of the other major functions of LDL would be to carry Co Q 10 because I’m not sure all the muscle cells are capable of making the Co Q 10 that they need for mitochondrial function and but you’re right LDL is a carrier molecule not just for triglycerides and cholesterol per se but for many antioxidants fat soluble vitamins Co Q 10 yeah and I do know that you have all these phospholipids as well that our I think it’s a that make up the cell wall and so we have a transport system of cholesterol cholesterol doesn’t just float around by itself it needs to be transported and I think that if you could just touch a little bit on the the necessary function of LDL that’s one area I wanted to want to touch on and then also I want you to maybe mention a little bit about statins and what the problem with statins that you run into I’m sure that you know it’s a hot topic with in your field I mean I’m a lot of cardiologists prescribe them right so let’s first talk about cholesterol in general and then move on to allyl cholesterol in particular cholesterol in general is an extremely important molecule for life there is no life on earth without cholesterol every living cell has cholesterol if you go back to some of the earliest parts of evolution when we started out as single-celled beings in this world those single cells also had cholesterol really if you look at cholesterol it is an integral part of every cell membrane the cell membrane gets its structural integrity the fluidity so that it acts as a barrier because cholesterol is connecting the phospholipids in such a way that it is providing those functions the second major way to think about cholesterol is to look at brain function because in our brain there are these cholesterol rafts and these rafts are locations where neurotransmitters set so the structural integrity of the neurotransmitter receptors is because of these cholesterol rafts and if you deprive the brain of cholesterol the integrity of these neurotransmitter receptors is affected so there is a lot of data that comes out and says that there are certain statins that cross the blood-brain barrier can have significant cognitive dysfunction - and in fact cholesterol is so important for the brain that it does not delegate the responsibility to any other organ to make cholesterol it makes its own Wow and I often joke that I would not be able to deal with the stress of being a cardiologist or giving this podcast if it were not for cholesterol because the LDL molecule is supplying cholesterol as raw material to my adrenal gland so that it can make the stress hormone which is called cortisone and and that’s an absolutely amazing fact that many of the hormones the backbone of that is a cholesterol molecule and the carrier molecule that is supplying that cholesterol to make that is the LDL and I often joke to audiences saying that hey men look handsome because of LDL cholesterol I like that and the reason is is because the LDL is the one that is supplying testes with cholesterol the raw material to make testosterone and similarly women look beautiful because their ovaries also need cholesterol to convert cholesterol to estrogens so these are functions that are sometimes completely skimmed over when we tried to knock the LDL down like crazy and say hey we the lowest is better and it made no sense to me as a cardiologist because I’ve been practicing for 30 years and I have seen people come in having extensive three vessels heart disease with blockages everywhere with cholesterol levels as low as 50 Wow Wow and I have seen 90 year old women or older with LDL cholestero